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Chromatin accessibility analysis identifies GSTM1 as a prognostic marker in human glioblastoma patients

BACKGROUND: Glioblastoma (GBM) is a malignant human brain tumor that has an extremely poor prognosis. Classic mutations such as IDH (isocitrate dehydrogenase) mutations, EGFR (epidermal growth factor receptor) alternations, and MGMT (O6-methylguanine-methyltransferase) promoter hypermethylation have...

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Detalles Bibliográficos
Autores principales: Huang, Yin-Cheng, Lai, Joseph Chieh-Yu, Peng, Pei-Hua, Wei, Kuo-Chen, Wu, Kou-Juey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565064/
https://www.ncbi.nlm.nih.gov/pubmed/34732244
http://dx.doi.org/10.1186/s13148-021-01181-8