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The apolipoprotein receptor LRP3 compromises APP levels

BACKGROUND: Members of the low-density lipoprotein (LDL) receptor family are involved in endocytosis and in transducing signals, but also in amyloid precursor protein (APP) processing and β-amyloid secretion. ApoER2/LRP8 is a member of this family with key roles in synaptic plasticity in the adult b...

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Detalles Bibliográficos
Autores principales: Cuchillo-Ibañez, Inmaculada, Lennol, Matthew P., Escamilla, Sergio, Mata-Balaguer, Trinidad, Valverde-Vozmediano, Lucía, Lopez-Font, Inmaculada, Ferrer, Isidro, Sáez-Valero, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565065/
https://www.ncbi.nlm.nih.gov/pubmed/34727970
http://dx.doi.org/10.1186/s13195-021-00921-5