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lncRNA SNHG1 induced by SP1 regulates bone remodeling and angiogenesis via sponging miR-181c-5p and modulating SFRP1/Wnt signaling pathway

BACKGROUND: We aimed to investigate the functions and underlying mechanism of lncRNA SNHG1 in bone differentiation and angiogenesis in the development of osteoporosis. METHODS: The differential gene or proteins expressions were measured by qPCR or western blot assays, respectively. The targeted rela...

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Detalles Bibliográficos
Autores principales: Yu, Xiao, Rong, Peng-Ze, Song, Meng-Sheng, Shi, Ze-Wen, Feng, Gong, Chen, Xian-Jun, Shi, Lin, Wang, Cheng-Hao, Pang, Qing-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565074/
https://www.ncbi.nlm.nih.gov/pubmed/34732133
http://dx.doi.org/10.1186/s10020-021-00392-2