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CRISPR/Cas9 genome editing reveals an essential role for basigin in maintaining a nonkeratinized squamous epithelium in cornea

One of the primary functions of nonkeratinized stratified squamous epithelia is to protect underlying tissues against chemical, microbial, and mechanical insult. Basigin is a transmembrane matrix metalloproteinase inducer commonly overexpressed during epithelial wound repair and cancer but whose phy...

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Detalles Bibliográficos
Autores principales: Woodward, Ashley M., Feeley, Marissa N., Rinaldi, Jamie, Argüeso, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565198/
https://www.ncbi.nlm.nih.gov/pubmed/34761172
http://dx.doi.org/10.1096/fba.2021-00067