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Rapid identification of methylase specificity (RIMS-seq) jointly identifies methylated motifs and generates shotgun sequencing of bacterial genomes

DNA methylation is widespread amongst eukaryotes and prokaryotes to modulate gene expression and confer viral resistance. 5-Methylcytosine (m5C) methylation has been described in genomes of a large fraction of bacterial species as part of restriction-modification systems, each composed of a methyltr...

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Detalles Bibliográficos
Autores principales: Baum, Chloé, Lin, Yu-Cheng, Fomenkov, Alexey, Anton, Brian P, Chen, Lixin, Yan, Bo, Evans, Thomas C, Roberts, Richard J, Tolonen, Andrew C, Ettwiller, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565308/
https://www.ncbi.nlm.nih.gov/pubmed/34417598
http://dx.doi.org/10.1093/nar/gkab705