Cargando…
Single molecule characterization of the binding kinetics of a transcription factor and its modulation by DNA sequence and methylation
The interaction of transcription factors with their response elements in DNA is emerging as a highly complex process, whose characterization requires measuring the full distribution of binding and dissociation times in a well-controlled assay. Here, we present a single-molecule assay that exploits t...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565314/ https://www.ncbi.nlm.nih.gov/pubmed/34606618 http://dx.doi.org/10.1093/nar/gkab843 |