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Modulation of the intrinsic chromatin binding property of HIV-1 integrase by LEDGF/p75
The stable insertion of the retroviral genome into the host chromosomes requires the association between integration complexes and cellular chromatin via the interaction between retroviral integrase and the nucleosomal target DNA. This final association may involve the chromatin-binding properties o...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565322/ https://www.ncbi.nlm.nih.gov/pubmed/34634812 http://dx.doi.org/10.1093/nar/gkab886 |