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Modulation of the intrinsic chromatin binding property of HIV-1 integrase by LEDGF/p75

The stable insertion of the retroviral genome into the host chromosomes requires the association between integration complexes and cellular chromatin via the interaction between retroviral integrase and the nucleosomal target DNA. This final association may involve the chromatin-binding properties o...

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Detalles Bibliográficos
Autores principales: Lapaillerie, Delphine, Lelandais, Benoît, Mauro, Eric, Lagadec, Floriane, Tumiotto, Camille, Miskey, Csaba, Ferran, Guillaume, Kuschner, Natacha, Calmels, Christina, Métifiot, Mathieu, Rooryck, Caroline, Ivics, Zoltan, Ruff, Marc, Zimmer, Christophe, Lesbats, Paul, Toutain, Jérôme, Parissi, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565322/
https://www.ncbi.nlm.nih.gov/pubmed/34634812
http://dx.doi.org/10.1093/nar/gkab886