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The RNA chaperone StpA enables fast RNA refolding by destabilization of mutually exclusive base pairs within competing secondary structure elements

In bacteria RNA gene regulatory elements refold dependent on environmental clues between two or more long-lived conformational states each associated with a distinct regulatory state. The refolding kinetics are strongly temperature-dependent and especially at lower temperatures they reach timescales...

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Detalles Bibliográficos
Autores principales: Hohmann, Katharina F, Blümler, Anja, Heckel, Alexander, Fürtig, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565331/
https://www.ncbi.nlm.nih.gov/pubmed/34614185
http://dx.doi.org/10.1093/nar/gkab876