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Epitome: predicting epigenetic events in novel cell types with multi-cell deep ensemble learning

The accumulation of large epigenomics data consortiums provides us with the opportunity to extrapolate existing knowledge to new cell types and conditions. We propose Epitome, a deep neural network that learns similarities of chromatin accessibility between well characterized reference cell types an...

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Detalles Bibliográficos
Autores principales: Morrow, Alyssa Kramer, Hughes, John Weston, Singh, Jahnavi, Joseph, Anthony Douglas, Yosef, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565335/
https://www.ncbi.nlm.nih.gov/pubmed/34379786
http://dx.doi.org/10.1093/nar/gkab676