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The phage defence island of a multidrug resistant plasmid uses both BREX and type IV restriction for complementary protection from viruses

Bacteria have evolved a multitude of systems to prevent invasion by bacteriophages and other mobile genetic elements. Comparative genomics suggests that genes encoding bacterial defence mechanisms are often clustered in ‘defence islands’, providing a concerted level of protection against a wider ran...

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Detalles Bibliográficos
Autores principales: Picton, David M, Luyten, Yvette A, Morgan, Richard D, Nelson, Andrew, Smith, Darren L, Dryden, David T F, Hinton, Jay C D, Blower, Tim R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565348/
https://www.ncbi.nlm.nih.gov/pubmed/34657954
http://dx.doi.org/10.1093/nar/gkab906