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The comprehensive interactomes of human adenosine RNA methyltransferases and demethylases reveal distinct functional and regulatory features

N6-methyladenosine (m(6)A) and N6,2′-O-dimethyladenosine (m(6)Am) are two abundant modifications found in mRNAs and ncRNAs that can regulate multiple aspects of RNA biology. They function mainly by regulating interactions with specific RNA-binding proteins. Both modifications are linked to developme...

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Detalles Bibliográficos
Autores principales: Covelo-Molares, Helena, Obrdlik, Ales, Poštulková, Ivana, Dohnálková, Michaela, Gregorová, Pavlína, Ganji, Ranjani, Potěšil, David, Gawriyski, Lisa, Varjosalo, Markku, Vaňáčová, Štěpánka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565353/
https://www.ncbi.nlm.nih.gov/pubmed/34634806
http://dx.doi.org/10.1093/nar/gkab900