Cargando…
The comprehensive interactomes of human adenosine RNA methyltransferases and demethylases reveal distinct functional and regulatory features
N6-methyladenosine (m(6)A) and N6,2′-O-dimethyladenosine (m(6)Am) are two abundant modifications found in mRNAs and ncRNAs that can regulate multiple aspects of RNA biology. They function mainly by regulating interactions with specific RNA-binding proteins. Both modifications are linked to developme...
Autores principales: | Covelo-Molares, Helena, Obrdlik, Ales, Poštulková, Ivana, Dohnálková, Michaela, Gregorová, Pavlína, Ganji, Ranjani, Potěšil, David, Gawriyski, Lisa, Varjosalo, Markku, Vaňáčová, Štěpánka |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565353/ https://www.ncbi.nlm.nih.gov/pubmed/34634806 http://dx.doi.org/10.1093/nar/gkab900 |
Ejemplares similares
-
N6-methyladenosine demethylase FTO targets pre-mRNAs and regulates alternative splicing and 3′-end processing
por: Bartosovic, Marek, et al.
Publicado: (2017) -
RNA methylation in nuclear pre‐mRNA processing
por: Covelo‐Molares, Helena, et al.
Publicado: (2018) -
Physical and functional interactome atlas of human receptor tyrosine kinases
por: Salokas, Kari, et al.
Publicado: (2022) -
Interplays of different types of epitranscriptomic mRNA modifications
por: Rengaraj, Praveenkumar, et al.
Publicado: (2021) -
Inhibitors of Protein Methyltransferases and Demethylases
por: Kaniskan, H. Ümit, et al.
Publicado: (2017)