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LukS-PV Induces Apoptosis via the SET8-H4K20me1-PIK3CB Axis in Human Acute Myeloid Leukemia Cells

Evidence suggests that histone modification disorders are involved in leukemia pathogenesis. We previously reported that LukS-PV, a component of Panton–Valentine leukocidin (PVL), has antileukemia activities that can induce differentiation, increase apoptosis, and inhibit proliferation of acute myel...

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Detalles Bibliográficos
Autores principales: Xu, Liang Fei, Shi, Lan, Zhang, Shan Shan, Ding, Peng Sheng, Ma, Fan, Song, Kai Di, Qiang, Ping, Chang, Wen Jiao, Dai, Yuan Yuan, Mei, Yi De, Ma, Xiao Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565356/
https://www.ncbi.nlm.nih.gov/pubmed/34745943
http://dx.doi.org/10.3389/fonc.2021.718791