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Late-stage modification of peptides and proteins at cysteine with diaryliodonium salts

The modification of peptides and proteins has emerged as a powerful means to efficiently prepare high value bioconjugates for a range of applications in chemical biology and for the development of next-generation therapeutics. Herein, we report a novel method for the chemoselective late-stage modifi...

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Detalles Bibliográficos
Autores principales: Byrne, Stephen A., Bedding, Max J., Corcilius, Leo, Ford, Daniel J., Zhong, Yichen, Franck, Charlotte, Larance, Mark, Mackay, Joel P., Payne, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565360/
https://www.ncbi.nlm.nih.gov/pubmed/34760200
http://dx.doi.org/10.1039/d1sc03127a