An enzyme-mediated bioorthogonal labeling method for genome-wide mapping of 5-hydroxymethyluracil

DNA 5-hydroxymethyluracil (5hmU) is a thymine modification existing in the genomes of various organisms. The post-replicative formation of 5hmU occurs via hydroxylation of thymine by ten-eleven translocation (TET) dioxygenases in mammals and J-binding proteins (JBPs) in protozoans, respectively. In...

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Detalles Bibliográficos
Autores principales: Ma, Cheng-Jie, Li, Lin, Shao, Wen-Xuan, Ding, Jiang-Hui, Cai, Xiao-Li, Lun, Zhao-Rong, Yuan, Bi-Feng, Feng, Yu-Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565368/
https://www.ncbi.nlm.nih.gov/pubmed/34760197
http://dx.doi.org/10.1039/d1sc03812e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565368/
https://www.ncbi.nlm.nih.gov/pubmed/34760197
http://dx.doi.org/10.1039/d1sc03812e

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