Allosteric inhibition of SARS-CoV-2 3CL protease by colloidal bismuth subcitrate

The SARS-CoV-2 3-chymotrypsin-like protease (3CLpro or Mpro) is a key cysteine protease for viral replication and transcription, making it an attractive target for antiviral therapies to combat the COVID-19 disease. Here, we demonstrate that bismuth drug colloidal bismuth subcitrate (CBS) is a poten...

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Detalles Bibliográficos
Autores principales: Tao, Xuan, Zhang, Lu, Du, Liubing, Liao, Ruyan, Cai, Huiling, Lu, Kai, Zhao, Zhennan, Xie, Yanxuan, Wang, Pei-Hui, Pan, Ji-An, Zhang, Yuebin, Li, Guohui, Dai, Jun, Mao, Zong-Wan, Xia, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565384/
https://www.ncbi.nlm.nih.gov/pubmed/34760193
http://dx.doi.org/10.1039/d1sc03526f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565384/
https://www.ncbi.nlm.nih.gov/pubmed/34760193
http://dx.doi.org/10.1039/d1sc03526f

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