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Allosteric inhibition of SARS-CoV-2 3CL protease by colloidal bismuth subcitrate
The SARS-CoV-2 3-chymotrypsin-like protease (3CLpro or Mpro) is a key cysteine protease for viral replication and transcription, making it an attractive target for antiviral therapies to combat the COVID-19 disease. Here, we demonstrate that bismuth drug colloidal bismuth subcitrate (CBS) is a poten...
Autores principales: | Tao, Xuan, Zhang, Lu, Du, Liubing, Liao, Ruyan, Cai, Huiling, Lu, Kai, Zhao, Zhennan, Xie, Yanxuan, Wang, Pei-Hui, Pan, Ji-An, Zhang, Yuebin, Li, Guohui, Dai, Jun, Mao, Zong-Wan, Xia, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565384/ https://www.ncbi.nlm.nih.gov/pubmed/34760193 http://dx.doi.org/10.1039/d1sc03526f |
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