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TGF-β1-overexpressing mesenchymal stem cells reciprocally regulate Th17/Treg cells by regulating the expression of IFN-γ

Transforming growth factor (TGF)-β1 and mesenchymal stromal cells (MSCs) are two effective immunosuppressive agents for organ transplantation technology. This study aims to explore the molecular mechanism of TGF-β1-overexpressed MSCs on T cell immunosuppression. To achieve that, BM-MSCs were isolate...

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Detalles Bibliográficos
Autores principales: Li, Ruixue, Wang, Renyong, Zhong, Shijie, Asghar, Farhan, Li, Tiehan, Zhu, Lei, Zhu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565592/
https://www.ncbi.nlm.nih.gov/pubmed/34761110
http://dx.doi.org/10.1515/biol-2021-0118