Elevated IgA and IL-10 levels in very-early-onset inflammatory bowel disease secondary to IL-10 receptor deficiency

OBJECTIVE: To report two patients with very-early-onset inflammatory bowel disease (VEOIBD) secondary to interleukin-10 receptor (IL-10R) mutations, explore immunophenotyping data and plasma cytokine profile on these cases compared to healthy controls, and describe the phenotype of IL-10/IL-10R muta...

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Detalles Bibliográficos
Autores principales: Sandy, Natascha Silva, Marega, Lia Furlaneto, Bechara, Giane Dantas, Riccetto, Adriana Gut Lopes, Bonfim, Carmen, Vilela, Maria Marluce dos Santos, Ribeiro, Antonio Fernando, Servidoni, Maria De Fatima, Lomazi, Elizete Aparecida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade de Pediatria de São Paulo 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565602/
https://www.ncbi.nlm.nih.gov/pubmed/34730757
http://dx.doi.org/10.1590/1984-0462/2022/40/2020434