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Identification of novel modulators of a schistosome transient receptor potential channel targeted by praziquantel

Given the worldwide burden of neglected tropical diseases, there is ongoing need to develop novel anthelmintic agents to strengthen the pipeline of drugs to combat these burdensome infections. Many diseases caused by parasitic flatworms are treated using the anthelmintic drug praziquantel (PZQ), emp...

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Detalles Bibliográficos
Autores principales: Chulkov, Evgeny G., Smith, Emery, Rohr, Claudia M., Yahya, Nawal A., Park, Sang-Kyu, Scampavia, Louis, Spicer, Timothy P., Marchant, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565742/
https://www.ncbi.nlm.nih.gov/pubmed/34731172
http://dx.doi.org/10.1371/journal.pntd.0009898