Lipid-induced DRAM recruits STOM to lysosomes and induces LMP to promote exosome release from hepatocytes in NAFLD

The biogenesis and diagnostic value of exosomes in nonalcoholic fatty liver disease (NAFLD) are unclear. In this study, we revealed that the plasma exosome level was higher in patients with NAFLD than that in healthy controls. Damage-regulated autophagy modulator (DRAM) was identified as one of the...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Tan, Jie, Wang, Mengke, Wang, Yifen, Dong, Mengzhen, Ma, Xuefeng, Sun, Baokai, Liu, Shousheng, Zhao, Zhenzhen, Chen, Lizhen, Liu, Kai, Xin, Yongning, Zhuang, Likun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565908/
https://www.ncbi.nlm.nih.gov/pubmed/34731006
http://dx.doi.org/10.1126/sciadv.abh1541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565908/
https://www.ncbi.nlm.nih.gov/pubmed/34731006
http://dx.doi.org/10.1126/sciadv.abh1541

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