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Noncoding loci without epigenomic signals can be essential for maintaining global chromatin organization and cell viability

Most noncoding regions of the human genome do not harbor any annotated element and are even not marked with any epigenomic or protein binding signal. However, an overlooked aspect of their possible role in stabilizing 3D chromatin organization has not been extensively studied. To illuminate their st...

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Detalles Bibliográficos
Autores principales: Ding, Bo, Liu, Ying, Liu, Zhiheng, Zheng, Lina, Xu, Ping, Chen, Zhao, Wu, Peiyao, Zhao, Ying, Pan, Qian, Guo, Yu, Wei, Wensheng, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565911/
https://www.ncbi.nlm.nih.gov/pubmed/34731001
http://dx.doi.org/10.1126/sciadv.abi6020