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Noncoding loci without epigenomic signals can be essential for maintaining global chromatin organization and cell viability
Most noncoding regions of the human genome do not harbor any annotated element and are even not marked with any epigenomic or protein binding signal. However, an overlooked aspect of their possible role in stabilizing 3D chromatin organization has not been extensively studied. To illuminate their st...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565911/ https://www.ncbi.nlm.nih.gov/pubmed/34731001 http://dx.doi.org/10.1126/sciadv.abi6020 |