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The Role of BTK Inhibition in the Treatment of Chronic Lymphocytic Leukemia: A Clinical View

The B cell receptor (BCR) signaling pathway is functional and has critical cell survival implications in B cell malignancies, such as chronic lymphocytic leukemia (CLL). Orally administered small molecule tyrosine kinase inhibitors of members of the BCR signaling pathway have proven to be transforma...

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Detalles Bibliográficos
Autores principales: Tambaro, Francesco Paolo, De Novellis, Danilo, Wierda, William G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565990/
https://www.ncbi.nlm.nih.gov/pubmed/34744463
http://dx.doi.org/10.2147/JEP.S265284