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Design and implementation of a microfluidic device capable of temporal growth factor delivery reveal filtering capabilities of the EGFR/ERK pathway

Utilizing microfluidics to mimic the dynamic temporal changes of growth factor and cytokine concentrations in vivo has greatly increased our understanding of how signal transduction pathways are structured to encode extracellular stimuli. To date, these devices have focused on delivering pulses of v...

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Detalles Bibliográficos
Autores principales: Krause, Harris B., Bondarowicz, Hanna, Karls, Alexis L., McClean, Megan N., Kreeger, Pamela K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566012/
https://www.ncbi.nlm.nih.gov/pubmed/34765858
http://dx.doi.org/10.1063/5.0059011