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Synthesis of aspirin-curcumin mimic conjugates of potential antitumor and anti-SARS-CoV-2 properties

Series of piperidone-salicylate conjugates were synthesized through the reaction of 3E,5E-bis(arylidene)-4-piperidones with the appropriate acid chloride of acetylsalicylate in the presence of triethylamine. All the synthesized conjugates reveal antiproliferative properties against A431 (squamous sk...

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Detalles Bibliográficos
Autores principales: Srour, Aladdin M., Panda, Siva S., Mostafa, Ahmed, Fayad, Walid, El-Manawaty, May A., A. F. Soliman, Ahmed, Moatasim, Yassmin, El Taweel, Ahmed, Abdelhameed, Mohamed F., Bekheit, Mohamed S., Ali, Mohamed A., Girgis, Adel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566089/
https://www.ncbi.nlm.nih.gov/pubmed/34775204
http://dx.doi.org/10.1016/j.bioorg.2021.105466