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Growth factor signaling predicts therapy resistance mechanisms and defines neuroblastoma subtypes
Neuroblastoma (NB) has a low frequency of recurrent mutations compared to other cancers, which hinders the development of targeted therapies and novel risk stratification strategies. Multikinase inhibitors have shown potential in treating high-risk NB, but their efficacy is likely impaired by the ca...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566230/ https://www.ncbi.nlm.nih.gov/pubmed/34556815 http://dx.doi.org/10.1038/s41388-021-02018-7 |