Mutant collagen COL11A1 enhances cancerous invasion

Collagens are the most abundant proteins in the body and comprise the basement membranes and stroma through which cancerous invasion occurs; however, a pro-neoplastic function for mutant collagens is undefined. Here we identify COL11A1 mutations in 66 of 100 cutaneous squamous cell carcinomas (cSCCs...

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Detalles Bibliográficos
Autores principales: Lee, Carolyn S., Siprashvili, Zurab, Mah, Angela, Bencomo, Tomas, Elcavage, Lara E., Che, Yonglu, Shenoy, Rajani M., Aasi, Sumaira Z., Khavari, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566234/
https://www.ncbi.nlm.nih.gov/pubmed/34584216
http://dx.doi.org/10.1038/s41388-021-02013-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566234/
https://www.ncbi.nlm.nih.gov/pubmed/34584216
http://dx.doi.org/10.1038/s41388-021-02013-y

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