Rituximab plus leflunomide in rheumatoid arthritis: a randomized, placebo-controlled, investigator-initiated clinical trial (AMARA study)

OBJECTIVE: To investigate the efficacy and safety of rituximab + LEF in patients with RA. METHODS: In this investigator-initiated, randomized, double-blind, placebo-controlled phase 3 trial, patients with an inadequate response to LEF who had failed one or more DMARD were randomly assigned 2:1 to i....

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Detalles Bibliográficos
Autores principales: Behrens, Frank, Koehm, Michaela, Rossmanith, Tanja, Alten, Rieke, Aringer, Martin, Backhaus, Marina, Burmester, Gerd R, Feist, Eugen, Herrmann, Eva, Kellner, Herbert, Krueger, Klaus, Lehn, Annette, Müller-Ladner, Ulf, Rubbert-Roth, Andrea, Tony, Hans-Peter, Wassenberg, Siegfried, Burkhardt, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Clinical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566251/
https://www.ncbi.nlm.nih.gov/pubmed/33738492
http://dx.doi.org/10.1093/rheumatology/keab153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566251/
https://www.ncbi.nlm.nih.gov/pubmed/33738492
http://dx.doi.org/10.1093/rheumatology/keab153

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