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Mechanical Pressure Driving Proteoglycan Expression in Mammographic Density: a Self-perpetuating Cycle?

Regions of high mammographic density (MD) in the breast are characterised by a proteoglycan (PG)-rich fibrous stroma, where PGs mediate aligned collagen fibrils to control tissue stiffness and hence the response to mechanical forces. Literature is accumulating to support the notion that mechanical s...

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Detalles Bibliográficos
Autores principales: Reye, Gina, Huang, Xuan, Haupt, Larisa M., Murphy, Ryan J., Northey, Jason J., Thompson, Erik W., Momot, Konstantin I., Hugo, Honor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566410/
https://www.ncbi.nlm.nih.gov/pubmed/34449016
http://dx.doi.org/10.1007/s10911-021-09494-3