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Encounters in Three Dimensions: How Nuclear Topology Shapes Genome Integrity

Almost 25 years ago, the phosphorylation of a chromatin component, histone H2AX, was discovered as an integral part of the DNA damage response in eukaryotes. Much has been learned since then about the control of DNA repair in the context of chromatin. Recent technical and computational advances in i...

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Detalles Bibliográficos
Autores principales: Sebastian, Robin, Aladjem, Mirit I., Oberdoerffer, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566435/
https://www.ncbi.nlm.nih.gov/pubmed/34745220
http://dx.doi.org/10.3389/fgene.2021.746380