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Encounters in Three Dimensions: How Nuclear Topology Shapes Genome Integrity
Almost 25 years ago, the phosphorylation of a chromatin component, histone H2AX, was discovered as an integral part of the DNA damage response in eukaryotes. Much has been learned since then about the control of DNA repair in the context of chromatin. Recent technical and computational advances in i...
Autores principales: | Sebastian, Robin, Aladjem, Mirit I., Oberdoerffer, Philipp |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566435/ https://www.ncbi.nlm.nih.gov/pubmed/34745220 http://dx.doi.org/10.3389/fgene.2021.746380 |
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