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Trametinib Inhibits the Growth and Aerobic Glycolysis of Glioma Cells by Targeting the PKM2/c-Myc Axis

Gliomas are primary tumors originating from glial progenitor cells. Traditional treatments, including surgery, radiotherapy, and chemotherapy, have many limitations concerning the prognosis of patients with gliomas. Therefore, it is important to find novel drugs to effectively treat gliomas. Trameti...

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Detalles Bibliográficos
Autores principales: Gao, Mingjun, Yang, Jin, Gong, Hailong, Lin, Yuancai, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566436/
https://www.ncbi.nlm.nih.gov/pubmed/34744739
http://dx.doi.org/10.3389/fphar.2021.760055