Cargando…
Trametinib Inhibits the Growth and Aerobic Glycolysis of Glioma Cells by Targeting the PKM2/c-Myc Axis
Gliomas are primary tumors originating from glial progenitor cells. Traditional treatments, including surgery, radiotherapy, and chemotherapy, have many limitations concerning the prognosis of patients with gliomas. Therefore, it is important to find novel drugs to effectively treat gliomas. Trameti...
Autores principales: | Gao, Mingjun, Yang, Jin, Gong, Hailong, Lin, Yuancai, Liu, Jing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566436/ https://www.ncbi.nlm.nih.gov/pubmed/34744739 http://dx.doi.org/10.3389/fphar.2021.760055 |
Ejemplares similares
-
KITENIN promotes aerobic glycolysis through PKM2 induction by upregulating the c-Myc/hnRNPs axis in colorectal cancer
por: Varlı, Mücahit, et al.
Publicado: (2023) -
MiR-1286 inhibits lung cancer growth through aerobic glycolysis by targeting PKM2
por: Li, Hui, et al.
Publicado: (2019) -
Shikonin Inhibits Tumor Growth of ESCC by suppressing PKM2 mediated Aerobic Glycolysis and STAT3 Phosphorylation
por: Zhang, Qiqi, et al.
Publicado: (2021) -
PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis
por: Liu, Fabao, et al.
Publicado: (2017) -
Oxymatrine Inhibits Colorectal Cancer Metastasis via Attenuating PKM2-Mediated Aerobic Glycolysis
por: Li, Xiaoping, et al.
Publicado: (2020)