Salt inducible kinases 2 and 3 are required for thymic T cell development

Salt Inducible Kinases (SIKs), of which there are 3 isoforms, are established to play roles in innate immunity, metabolic control and neuronal function, but their role in adaptive immunity is unknown. To address this gap, we used a combination of SIK knockout and kinase-inactive knock-in mice. The c...

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Detalles Bibliográficos
Autores principales: Nefla, Meriam, Darling, Nicola J., van Gijsel Bonnello, Manuel, Cohen, Philip, Arthur, J. Simon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566462/
https://www.ncbi.nlm.nih.gov/pubmed/34732767
http://dx.doi.org/10.1038/s41598-021-00986-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566462/
https://www.ncbi.nlm.nih.gov/pubmed/34732767
http://dx.doi.org/10.1038/s41598-021-00986-0

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