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Thioredoxin-1 mediates neuroprotection of Schisanhenol against MPP(+)-induced apoptosis via suppression of ASK1-P38-NF-κB pathway in SH-SY5Y cells
Oxidative stress-induced dopaminergic neuronal loss and apoptosis play a crucial role in the pathogenesis of Parkinson’s disease (PD), and as a vital antioxidant protein, thioredoxin (Trx) exerts neuroprotection against PD. In this study, we investigated the effect of Schisanhenol (Sal), an active c...
Autores principales: | Yang, Hongyan, Li, Libo, Jiao, Yu, Zhang, Yuanliang, Wang, Yuhua, Zhu, Kunjie, Sun, Chao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566484/ https://www.ncbi.nlm.nih.gov/pubmed/34732784 http://dx.doi.org/10.1038/s41598-021-01000-3 |
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