The chemotherapeutic drug carboplatin affects macrophage responses to LPS and LPS tolerance via epigenetic modifications

Following re-exposure to lipopolysaccharide (LPS), macrophages exhibit an immunosuppressive state known as LPS tolerance, which is characterized by repressed proinflammatory cytokine production. LPS-induced tolerance in macrophages is mediated in part by epigenetic changes. Carboplatin, an anticance...

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Detalles Bibliográficos
Autores principales: Boonmee, Atsadang, Benjaskulluecha, Salisa, Kueanjinda, Patipark, Wongprom, Benjawan, Pattarakankul, Thitiporn, Palaga, Tanapat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566489/
https://www.ncbi.nlm.nih.gov/pubmed/34732786
http://dx.doi.org/10.1038/s41598-021-00955-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566489/
https://www.ncbi.nlm.nih.gov/pubmed/34732786
http://dx.doi.org/10.1038/s41598-021-00955-7

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