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The chemotherapeutic drug carboplatin affects macrophage responses to LPS and LPS tolerance via epigenetic modifications
Following re-exposure to lipopolysaccharide (LPS), macrophages exhibit an immunosuppressive state known as LPS tolerance, which is characterized by repressed proinflammatory cytokine production. LPS-induced tolerance in macrophages is mediated in part by epigenetic changes. Carboplatin, an anticance...
Autores principales: | Boonmee, Atsadang, Benjaskulluecha, Salisa, Kueanjinda, Patipark, Wongprom, Benjawan, Pattarakankul, Thitiporn, Palaga, Tanapat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566489/ https://www.ncbi.nlm.nih.gov/pubmed/34732786 http://dx.doi.org/10.1038/s41598-021-00955-7 |
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