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Agrin-Matrix Metalloproteinase-12 axis confers a mechanically competent microenvironment in skin wound healing

An orchestrated wound healing program drives skin repair via collective epidermal cell proliferation and migration. However, the molecular determinants of the tissue microenvironment supporting wound healing remain poorly understood. Herein we discover that proteoglycan Agrin is enriched within the...

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Detalles Bibliográficos
Autores principales: Chakraborty, Sayan, Sampath, Divyaleka, Yu Lin, Melissa Ong, Bilton, Matthew, Huang, Cheng-Kuang, Nai, Mui Hoon, Njah, Kizito, Goy, Pierre-Alexis, Wang, Cheng-Chun, Guccione, Ernesto, Lim, Chwee-Teck, Hong, Wanjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566503/
https://www.ncbi.nlm.nih.gov/pubmed/34732729
http://dx.doi.org/10.1038/s41467-021-26717-7