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Saikosaponin D Attenuates Pancreatic Injury Through Suppressing the Apoptosis of Acinar Cell via Modulation of the MAPK Signaling Pathway

Chronic pancreatitis (CP) is a progressive fibro-inflammatory syndrome. The damage of acinar cells is the main cause of inflammation and the activation of pancreatic stellate cells (PSCs), which can thereby possibly further aggravate the apoptosis of more acinar cells. Saikosaponind (SSd), a major a...

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Detalles Bibliográficos
Autores principales: Li, Caixia, Cui, Lihua, Zhang, Lanqiu, Yang, Lei, Zhuo, Yuzhen, Cui, Jialin, Cui, Naiqiang, Zhang, Shukun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566544/
https://www.ncbi.nlm.nih.gov/pubmed/34744719
http://dx.doi.org/10.3389/fphar.2021.735079