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Estimating DNA methylation potential energy landscapes from nanopore sequencing data
High-throughput third-generation nanopore sequencing devices have enormous potential for simultaneously observing epigenetic modifications in human cells over large regions of the genome. However, signals generated by these devices are subject to considerable noise that can lead to unsatisfactory de...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566571/ https://www.ncbi.nlm.nih.gov/pubmed/34732768 http://dx.doi.org/10.1038/s41598-021-00781-x |