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Estimating DNA methylation potential energy landscapes from nanopore sequencing data

High-throughput third-generation nanopore sequencing devices have enormous potential for simultaneously observing epigenetic modifications in human cells over large regions of the genome. However, signals generated by these devices are subject to considerable noise that can lead to unsatisfactory de...

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Detalles Bibliográficos
Autores principales: Abante, Jordi, Kambhampati, Sandeep, Feinberg, Andrew P., Goutsias, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566571/
https://www.ncbi.nlm.nih.gov/pubmed/34732768
http://dx.doi.org/10.1038/s41598-021-00781-x