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Progenitor translatome changes coordinated by Tsc1 increase perception of Wnt signals to end nephrogenesis
Mammalian nephron endowment is determined by the coordinated cessation of nephrogenesis in independent niches. Here we report that translatome analysis in Tsc1(+/−) nephron progenitor cells from mice with elevated nephron numbers reveals how differential translation of Wnt antagonists over agonists...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566581/ https://www.ncbi.nlm.nih.gov/pubmed/34732708 http://dx.doi.org/10.1038/s41467-021-26626-9 |