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Multiplexed immunofluorescence identifies high stromal CD68(+)PD-L1(+) macrophages as a predictor of improved survival in triple negative breast cancer

Triple negative breast cancer (TNBC) comprises 10–15% of all breast cancers and has a poor prognosis with a high risk of recurrence within 5 years. PD-L1 is an important biomarker for patient selection for immunotherapy but its cellular expression and co-localization within the tumour immune microen...

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Detalles Bibliográficos
Autores principales: Wang, James, Browne, Lois, Slapetova, Iveta, Shang, Fei, Lee, Kirsty, Lynch, Jodi, Beretov, Julia, Whan, Renee, Graham, Peter H., Millar, Ewan K. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566595/
https://www.ncbi.nlm.nih.gov/pubmed/34732817
http://dx.doi.org/10.1038/s41598-021-01116-6