Cargando…
Multiplexed immunofluorescence identifies high stromal CD68(+)PD-L1(+) macrophages as a predictor of improved survival in triple negative breast cancer
Triple negative breast cancer (TNBC) comprises 10–15% of all breast cancers and has a poor prognosis with a high risk of recurrence within 5 years. PD-L1 is an important biomarker for patient selection for immunotherapy but its cellular expression and co-localization within the tumour immune microen...
Autores principales: | Wang, James, Browne, Lois, Slapetova, Iveta, Shang, Fei, Lee, Kirsty, Lynch, Jodi, Beretov, Julia, Whan, Renee, Graham, Peter H., Millar, Ewan K. A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566595/ https://www.ncbi.nlm.nih.gov/pubmed/34732817 http://dx.doi.org/10.1038/s41598-021-01116-6 |
Ejemplares similares
-
TILs Immunophenotype in Breast Cancer Predicts Local Failure and Overall Survival: Analysis in a Large Radiotherapy Trial with Long-Term Follow-Up
por: Millar, Ewan, et al.
Publicado: (2020) -
Tumour Stroma Ratio Assessment Using Digital Image Analysis Predicts Survival in Triple Negative and Luminal Breast Cancer
por: Millar, Ewan KA, et al.
Publicado: (2020) -
Survival prediction in triple negative breast cancer using multiple instance learning of histopathological images
por: Sandarenu, Piumi, et al.
Publicado: (2022) -
Towards multiplexed immunofluorescence of 3D tissues
por: Cho, Wonjin, et al.
Publicado: (2023) -
Live Tissue Imaging to Elucidate Mechanical Modulation of Stem Cell Niche Quiescence
por: Yu, Nicole Y.C., et al.
Publicado: (2016)