Genetic variability affects the skeletal response to immobilization in founder strains of the diversity outbred mouse population

Mechanical unloading decreases bone volume and strength. In humans and mice, bone mineral density is highly heritable, and in mice the response to changes in loading varies with genetic background. Thus, genetic variability may affect the response of bone to unloading. As a first step to identify ge...

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Detalles Bibliográficos
Autores principales: Friedman, Michael A., Abood, Abdullah, Senwar, Bhavya, Zhang, Yue, Maroni, Camilla Reina, Ferguson, Virginia L., Farber, Charles R., Donahue, Henry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566767/
https://www.ncbi.nlm.nih.gov/pubmed/34761080
http://dx.doi.org/10.1016/j.bonr.2021.101140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566767/
https://www.ncbi.nlm.nih.gov/pubmed/34761080
http://dx.doi.org/10.1016/j.bonr.2021.101140

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