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Genetic variability affects the skeletal response to immobilization in founder strains of the diversity outbred mouse population
Mechanical unloading decreases bone volume and strength. In humans and mice, bone mineral density is highly heritable, and in mice the response to changes in loading varies with genetic background. Thus, genetic variability may affect the response of bone to unloading. As a first step to identify ge...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566767/ https://www.ncbi.nlm.nih.gov/pubmed/34761080 http://dx.doi.org/10.1016/j.bonr.2021.101140 |