Modeling C9orf72-Related Frontotemporal Dementia and Amyotrophic Lateral Sclerosis in Drosophila

An intronic hexanucleotide (GGGGCC) expansion in the C9orf72 gene is the most common genetic cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). In the decade following its discovery, much progress has been made in enhancing our understanding of how it precipitates diseas...

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Detalles Bibliográficos
Autores principales: Sharpe, Joanne L., Harper, Nikki S., Garner, Duncan R., West, Ryan J. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566814/
https://www.ncbi.nlm.nih.gov/pubmed/34744635
http://dx.doi.org/10.3389/fncel.2021.770937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566814/
https://www.ncbi.nlm.nih.gov/pubmed/34744635
http://dx.doi.org/10.3389/fncel.2021.770937

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