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Generation of Two Paclitaxel-Resistant High-Grade Serous Carcinoma Cell Lines With Increased Expression of P-Glycoprotein

Debulking surgery followed by chemotherapy are the standard of care for high-grade serous carcinoma. After an initial good response to treatment, the majority of patients relapse with a chemoresistant profile, leading to a poor overall survival. Chemotherapy regimens used in high-grade serous carcin...

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Detalles Bibliográficos
Autores principales: Nunes, Mariana, Silva, Patrícia M. A., Coelho, Ricardo, Pinto, Carla, Resende, Albina, Bousbaa, Hassan, Almeida, Gabriela M., Ricardo, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566917/
https://www.ncbi.nlm.nih.gov/pubmed/34745981
http://dx.doi.org/10.3389/fonc.2021.752127