Intranuclear Delivery of HIF-1α-TMD Alleviates EAE via Functional Conversion of TH17 Cells

T helper 17 (TH17) cells are involved in several autoimmune diseases such as multiple sclerosis (MS) and rheumatoid arthritis (RA). In addition to retinoic acid receptor-related orphan nuclear receptor gamma t (ROR-γt), hypoxia-inducible factor-1α (HIF-1α) is essential for the differentiation and in...

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Detalles Bibliográficos
Autores principales: Shin, Jin-Su, Kim, Ilkoo, Moon, Jae-Seung, Ho, Chun-Chang, Choi, Min-Sun, Ghosh, Sankar, Lee, Sang-Kyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566938/
https://www.ncbi.nlm.nih.gov/pubmed/34745114
http://dx.doi.org/10.3389/fimmu.2021.741938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566938/
https://www.ncbi.nlm.nih.gov/pubmed/34745114
http://dx.doi.org/10.3389/fimmu.2021.741938

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