Clemastine Ameliorates Myelin Deficits via Preventing Senescence of Oligodendrocytes Precursor Cells in Alzheimer’s Disease Model Mouse

Disrupted myelin and impaired myelin repair have been observed in the brains of patients and various mouse models of Alzheimer’s disease (AD). Clemastine, an H1-antihistamine, shows the capability to induce oligodendrocyte precursor cell (OPC) differentiation and myelin formation under different neu...

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Detalles Bibliográficos
Autores principales: Xie, Yuan-Yuan, Pan, Ting-Ting, Xu, De-en, Huang, Xin, Tang, Yong, Huang, Wenhui, Chen, Rui, Lu, Li, Chi, Hao, Ma, Quan-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567029/
https://www.ncbi.nlm.nih.gov/pubmed/34746130
http://dx.doi.org/10.3389/fcell.2021.733945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567029/
https://www.ncbi.nlm.nih.gov/pubmed/34746130
http://dx.doi.org/10.3389/fcell.2021.733945

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