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Estrogen receptor variant ERα46 and insulin receptor drive in primary breast cancer cells growth effects and interleukin 11 induction prompting the motility of cancer‐associated fibroblasts

Among the prognostic and predictive biomarkers of breast cancer (BC), the role of estrogen receptor (ER)α wild‐type has been acknowledged, although the action of certain ERα splice variants has not been elucidated. Insulin/insulin receptor (IR) axis has also been involved in the progression and meta...

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Detalles Bibliográficos
Autores principales: Cirillo, Francesca, Pellegrino, Michele, Talia, Marianna, Perrotta, Ida Daniela, Rigiracciolo, Damiano Cosimo, Spinelli, Asia, Scordamaglia, Domenica, Muglia, Lucia, Guzzi, Rita, Miglietta, Anna Maria, De Francesco, Ernestina Marianna, Belfiore, Antonino, Maggiolini, Marcello, Lappano, Rosamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567034/
https://www.ncbi.nlm.nih.gov/pubmed/34841688
http://dx.doi.org/10.1002/ctm2.516